Article

A simple approximation to bias in the genetic effect estimates when multiple disease states share a clinical diagnosis

2018-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Case-control genome-wide association (CC-GWAS) studies might provide valuable clues to the underlying pathophysiologic mechanisms of complex diseases, such as neurodegenerative disease, cancer. A commonly overlooked complication is that multiple distinct disease states might present with the same set of symptoms and hence share a clinical diagnosis. These disease states can only be distinguished...

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Literature Corpus work: ed61b773-d551-549a-92ea-68b3769a5c0f
DOI: 10.1101/483198

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