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Article

Case-only genome-wide interaction study of disease risk, prognosis and treatment.

Genetic epidemiology - 1 Jan 2010

Pierce Brandon L, Ahsan Habibul

Abstract excerpt

Case-control genome-wide association (GWA) studies have facilitated the identification of susceptibility loci for many complex diseases; however, these studies are often not adequately powered to detect gene-environment (G x E) and gene-gene (G x G) interactions. Case-only studies are more efficient than case-control studies for detecting interactions and require no data on control subjects. In this article, we...

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Identifiers

PMID: 19434715
DOI: 10.1002/gepi.20427
PMCID: PMC2861332

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