Article

Functional Connectivity Alterations in Spinocerebellar Ataxia Type 10: Insights from Gray Matter Atrophy

2025-03-19

Abstract excerpt

Spinocerebellar ataxia type 10 (SCA10) is a rare, inherited neurological disorder caused by an expansion of the non-coding ATTCT pentanucleotide repeat in the ATAXIN 10 gene. It is characterized by cerebellar ataxia and epilepsy. Previous research has demonstrated extensive white and gray matter degeneration, particularly in the cerebellum. However, the impact of the SCA10 mutation on functional connectivity (FC)...

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Literature Corpus work: b097b39d-cce7-5de9-951e-0212c02e149e
DOI: 10.1101/2025.03.19.644149

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