Article
Functional Connectivity Analysis in Heterozygous Glucocerebrosidase Mutation Carriers.
Journal of Parkinson's disease - 1 Jan 2021
Sezgin Mine, Kicik Ani, Bilgic Basar, Kurt Elif, Bayram Ali, Hanagası Hasmet, Tepgec Fatih, Toksoy Guven, Gurvit Hakan, Uyguner Oya, Gokcay Gulden, Demiralp Tamer, Emre Murat
Abstract excerpt
BACKGROUND: There is evidence that alterations in functional connectivity (FC) of the striatocortical circuits may appear before the onset of clinical symptoms of Parkinson's disease (PD). OBJECTIVE: The aim of this study was to investigate FC of the striatocortical circuitry in asymptomatic carriers of heterozygous glucocerebrosidase (GBA) mutations, which pose a significant risk for developing PD. METHODS:...
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