Article

Associations between CAG repeat size, brain and spinal cord volume loss, and motor symptoms in spinocerebellar ataxia type 3: a cohort study

2024-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Spinocerebellar ataxia type 3 (SCA3) is a hereditary polyglutamine disease, caused by abnormally expanded cytosine–adenine–guanine (CAG) repeats in <italic>ATXN3</italic> gene. It is classically characterized by cerebellar and spinal cord atrophy and presents with progressive ataxia. we here investigated the associations between expanded CAG repeat size, brain a...

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Literature Corpus work: 001353c7-8888-52ed-a9f0-96a679c2b5bb
DOI: 10.21203/rs.3.rs-4593982/v1

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