Article

Disrupted cerebellar structural connectome in spinocerebellar ataxia type 3 and its association with transcriptional profiles

2023-09-13

Abstract excerpt

Spinocerebellar ataxia type 3 (SCA3) is primarily characterized by progressive cerebellar degeneration, including gray matter atrophy and disrupted anatomical and functional connectivity of the cerebellum. The alterations of topological organization of cerebellar white matter structural network in SCA3 and the underlying neurobiological mechanism remain unknown. Using a cohort of 20 patients with SCA3 and 20 healt...

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Literature Corpus work: 17be3bbf-491f-5169-823c-8322bad850f2
DOI: 10.1101/2023.09.13.23295487

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