Article
Brain structure in asymptomatic FMR1 premutation carriers at risk for fragile X-associated tremor/ataxia syndrome.
Neurobiology of aging - 1 Jun 2013
Battistella Giovanni, Niederhauser Julien, Fornari Eleonora, Hippolyte Loyse, Gronchi Perrin Aline, Lesca Gaetan, Forzano Francesca, Hagmann Patric, Vingerhoets Francois J G, Draganski Bogdan, Maeder Philippe, Jacquemont Sébastien
Abstract excerpt
Fragile X-associated tremor/ataxia syndrome (FXTAS), a late-onset movement disorder affecting FMR1 premutation carriers, is associated with cerebral and cerebellar lesions. The aim of this study was to test whether computational anatomy can detect similar patterns in asymptomatic FMR1 premutation carriers (mean age 46.7 years) with qualitatively normal -appearing grey and white matter on brain MRI. We used a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.