Article
Structural changes associated with progression of motor deficits in spinocerebellar ataxia 17.
Cerebellum (London, England) - 1 Jun 2010
Reetz Kathrin, Lencer Rebekka, Hagenah Johannes M, Gaser Christian, Tadic Vera, Walter Uwe, Wolters Alexander, Steinlechner Susanne, Zühlke Christine, Brockmann Katja, Klein Christine, Rolfs Arndt, Binkofski Ferdinand
Abstract excerpt
Spinocerebellar ataxia (SCA17) is a rare genetic disorder characterized by a variety of neuropsychiatric symptoms. Recently, using magnetic resonance imaging (MRI) voxel-based morphometry (VBM), several specific functional-structural correlations comprising differential degeneration related to motor and psychiatric symptoms were reported in patients with SCA17. To investigate gray matter volume (GMV) changes over...
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