Article

<i>Tbx1</i> regulates extracellular matrix-cell interactions in the second heart field

2018-02-20

Abstract excerpt

<h4>SUMMARY</h4> Tbx1, the major candidate gene for DiGeorge or 22q11.2 deletion syndrome, is required for efficient incorporation of cardiac progenitors (CPs) of the second heart field (SHF) into the heart. However, the mechanisms by which TBX1 regulates this process are still unclear. Here, we have used two independent models, mouse embryos and cultured cells, to define the role of TBX1 in establishing morpholo...

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Literature Corpus work: b095d650-8540-51ff-9eb0-decb20c71396
DOI: 10.1101/267906

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