Article
Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.
Circulation research - 10 Oct 2014
Rana M Sameer, Théveniau-Ruissy Magali, De Bono Christopher, Mesbah Karim, Francou Alexandre, Rammah Mayyasa, Domínguez Jorge N, Roux Marine, Laforest Brigitte, Anderson Robert H, Mohun Timothy, Zaffran Stephane, Christoffels Vincent M, Kelly Robert G
Abstract excerpt
RATIONALE: Cardiac progenitor cells from the second heart field (SHF) contribute to rapid growth of the embryonic heart, giving rise to right ventricular and outflow tract (OFT) myocardium at the arterial pole of the heart, and atrial myocardium at the venous pole. Recent clonal analysis and cell-tracing experiments indicate that a common progenitor pool in the posterior region of the SHF gives rise to both OFT...
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