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Article

A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac field

1 Jul 2007

Abstract excerpt

Tbx1 is required for the expansion of second heart field (SHF) cardiac progenitors destined to the outflow tract of the heart. Loss of Tbx1 causes heart defects in humans and mice. We report a novel Tbx1(Cre) knock-in allele that we use to fate map Tbx1-expressing cells during development in conjunction with a reporter and 3D image reconstruction. Tbx1 descendants constitute a mesodermal cell population that...

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Identifiers

PMID: 17610275
DOI: 10.1002/dvg.20317

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A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac fieldPMID 17610275Read ↗

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Unique developmental trajectories and genetic regulation of ventricular and outflow tract progenitors in the zebrafish second heart fieldSemantic proximity Read ↗

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