Article

Confirmation of HLA-II associations with TB susceptibility in admixed African samples

2024-05-31

Abstract excerpt

The International Tuberculosis Host Genetics Consortium (ITHGC) demonstrated the power of large-scale GWAS analysis across diverse ancestries in identifying tuberculosis (TB) susceptibility loci. Despite identifying a significant genetic correlate in the human leukocyte antigen (HLA)-II region, this association did not replicate in the African ancestry-specific analysis, due to small sample size and the inclusion...

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Literature Corpus work: afd2af4f-bb7a-5178-825d-32f4a39d47bd
DOI: 10.1101/2024.05.30.24308060

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