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Article

Using multi-way admixture mapping to elucidate TB susceptibility in the South African Coloured population.

BMC genomics - 25 Nov 2014

Daya Michelle, van der Merwe Lize, Gignoux Christopher R, van Helden Paul D, Möller Marlo, Hoal Eileen G

Abstract excerpt

BACKGROUND: The admixed South African Coloured population is ideally suited to the discovery of tuberculosis susceptibility genetic variants and their probable ethnic origins, but previous attempts at finding such variants using genome-wide admixture mapping were hampered by the inaccuracy of local ancestry inference. In this study, we infer local ancestry using the novel algorithm implemented in RFMix, with the...

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PMID: 25422094
DOI: 10.1186/1471-2164-15-1021
PMCID: PMC4256931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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