Article

Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile

2022-07-10

Abstract excerpt

Several HLA allelic variants have been associated with protection from or susceptibility to infectious and autoimmune diseases. Here, we examined whether specific HLA alleles would be associated with different Mycobacterium tuberculosis (Mtb) infection outcomes. The HLA alleles present at the -A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1, and -DRB3/4/5 loci were determined in a cohort of 636 individuals with known...

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Literature Corpus work: 3cc8312a-d5bf-59aa-83ee-4ca78da57953
DOI: 10.1101/2022.07.06.22277293

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