Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population.

doi:10.1016/j.humimm.2017.04.006

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Article

Human leukocyte antigen class I (A, B and C) allele and haplotype variation in a South African Mixed ancestry population.

Human immunology - 1 Jan 2000

Loubser Shayne, Paximadis Maria, Tiemessen Caroline T

Abstract excerpt

South Africa has a large (∼53million), ethnically diverse population (black African, Caucasian, Indian/Asian and Mixed ancestry) and a high disease burden (particularly HIV-1 and Mycobacterium tuberculosis). The Mixed ancestry population constitutes ∼9% of the total population and was established ∼365years ago in the Western Cape region through interracial mixing of black Africans, Europeans and Asians. Admixed...

Topics

Alleles
Asian People
Black People
Gene Frequency
Genetic Predisposition to Disease
HIV Infections
HIV-1
HLA-A Antigens
HLA-B Antigens
HLA-C Antigens
Haplotypes
Humans
Polymorphism, Genetic
South Africa
White People

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Identifiers

PMID: 28438553
DOI: 10.1016/j.humimm.2017.04.006
PMCID: PMC5451074

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