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Article

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture.

eLife - 15 Jan 2024

Schurz Haiko, Naranbhai Vivek, Yates Tom A, Gilchrist James J, Parks Tom, Dodd Peter J, Möller Marlo, Hoal Eileen G, Morris Andrew P, Hill Adrian V S

Abstract excerpt

The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over 100 genes have been studied as candidates for TB susceptibility, and several variants were identified by genome-wide association studies (GWAS), but few replicate. We established the International Tuberculosis Host Genetics Consortium to perform a multi-ancestry meta-analysis of GWAS, including 14,153 cases and 19,536...

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Identifiers

PMID: 38224499
DOI: 10.7554/eLife.84394
PMCID: PMC10789494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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