Article

Spatially resolved immune exhaustion within the alloreactive microenvironment predicts liver transplant rejection.

2023-07-03

Abstract excerpt

<title>Abstract</title> <p>Allograft rejection is a frequent complication following solid organ transplantation, but defining specific immune subsets mediating alloimmunity has been elusive due to the scarcity of tissue in clinical biopsy specimens. Single cell techniques have emerged as valuable tools for studying mechanisms of disease in complex tissue microenvironments. Here, we developed a highly multiplexed...

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Literature Corpus work: afafd1fe-8d47-514f-b721-49ce8db51ac4
DOI: 10.21203/rs.3.rs-3044385/v1

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