Article

IMmuneCite: an integrated workflow for analysis of immune enriched spatial proteomic data

2024-07-09

Abstract excerpt

<title>Abstract</title> <p>Spatial proteomics enable detailed analysis of tissue at single cell resolution. However, creating reliable segmentation masks and assigning accurate cell phenotypes to discrete cellular phenotypes can be challenging. We introduce IMmuneCite, a computational framework for comprehensive image pre-processing and single-cell dataset creation, focused on defining complex immune landscapes w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77e26ae2-0e2e-55b6-a020-b18f97dfe12e
DOI: 10.21203/rs.3.rs-4571625/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

IMmuneCite: an integrated workflow for analysis of immune enriched spatial proteomic dataDOI 10.21203/rs.3.rs-4571625/v2Read

Spatially resolved immune exhaustion within the alloreactive microenvironment predicts liver transplant rejection.Semantic proximity Read

Single cell spatial proteomics maps human liver zonation patterns and their vulnerability to fibrosisSemantic proximity Read

A framework for ultra-low input spatial tissue proteomicsSemantic proximity Read

ImmuNet: A Segmentation-Free Machine Learning Pipeline for Immune Landscape Phenotyping in Tumors by Muliplex ImagingSemantic proximity Read

CellMAPS: A no-code model-based customisable multiplex image analysis workflowSemantic proximity Read

3-D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System (MANTIS)Semantic proximity Read

Tumor-Immune Partitioning and Clustering (TIPC) algorithm reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironmentSemantic proximity Read

An integrated single-cell atlas of checkpoint inhibitor-induced liver injury links shared liver-tumour CD8+ T cell clones to cytotoxicity and macrophage crosstalksSemantic proximity Read

Spatial single-cell proteomics landscape decodes the tumor microenvironmental ecosystem of intrahepatic cholangiocarcinomaSemantic proximity Read

Unveiling spatial complexity in solid tumor immune microenvironments through multiplexed imaging.Semantic proximity Read

AI-enabled Spatial Profiling of Circulating Tumor-Immune Ecosystems Predicts Patient Outcomes Across CancersSemantic proximity Read

MICRON learns outcome-associated representations of spatial immune microenvironmentsSemantic proximity Read