Article
Immune landscape in rejection of renal transplantation revealed by high-throughput single-cell RNA sequencing
20 Jul 2023
Abstract excerpt
Background: The role of the cellular level in kidney transplant rejection is unclear, and single-cell RNA sequencing (scRNA-seq) can reveal the single-cell landscape behind rejection of human kidney allografts at the single-cell level. Methods: High-quality transcriptomes were generated from scRNA-seq data from five human kidney transplantation biopsy cores. Cluster analysis was performed on the scRNA-seq data by...
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