Article

Inferring the intrinsic mutational fitness landscape of influenza-like evolving antigens from temporally ordered sequence data

2021-07-29

Abstract excerpt

There still are no effective long-term protective vaccines against viruses that continuously evolve under immune pressure such as seasonal influenza, which has caused, and can cause, devastating epidemics in the human population. For finding such a broadly protective immunization strategy it is useful to know how easily the virus can escape via mutation from specific antibody responses. This information is encoded...

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Literature Corpus work: af28c71c-7ed1-531f-8eaf-94611be26407
DOI: 10.1101/2021.07.28.454153

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