Article
Antigenic evolution of viruses in host populations.
PLoS pathogens - 1 Sept 2018
Rouzine Igor M, Rozhnova Ganna
Abstract excerpt
To escape immune recognition in previously infected hosts, viruses evolve genetically in immunologically important regions. The host's immune system responds by generating new memory cells recognizing the mutated viral strains. Despite recent advances in data collection and analysis, it remains conceptually unclear how epidemiology, immune response, and evolutionary factors interact to produce the observed speed...
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