Article

Simple models of non-random mating and environmental transmission bias standard human genetics statistical methods

2024-10-18

Abstract excerpt

There is recognition among human complex-trait geneticists that not only are many common assumptions made for the sake of statistical tractability (e.g., random mating, independence of parent/offspring environments) unlikely to apply in many contexts, but that methods reliant on such assumptions can yield misleading results, even in large samples. Investigations of the consequences of violating these assumptions s...

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Literature Corpus work: aedecfd0-2a47-5028-932b-8b9b9417a853
DOI: 10.1101/2024.10.16.618755

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