Article

RNA-seq analysis reveals transcriptome changes associated with the progression of non-alcoholic liver disease in livers from Efcab4b knockout mice

2024-05-30

Abstract excerpt

<title>Abstract</title> <p>EFCAB4B is an evolutionarily conserved protein that encodes for the Rab GTPase Rab46, and the CRAC channel modulator, CRACR2A. Previous genome wide association studies have demonstrated the association of EFCAB4B variants in the progression of non-alcoholic liver disease (NAFLD). In this study we show that mice with global depletion of Efcab4b-/-have significantly larger livers than the...

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Literature Corpus work: ae783276-70c5-597f-9978-8e033242929c
DOI: 10.21203/rs.3.rs-4425717/v1

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