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Article

Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling.

Cellular and molecular gastroenterology and hepatology - 1 Jan 2021

Choi Yeeun, Song Min-Ji, Jung Woong-Jae, Jeong Haengdueng, Park Seokjae, Yang Bobae, Lee Eun-Chong, Joo Jung-Sik, Choi Dahee, Koo Seung-Hoi, Kim Eun-Kyoung, Nam Ki Taek, Kim Hyoung-Pyo

Abstract excerpt

BACKGROUND & AIMS: The liver is the major organ for metabolizing lipids, and malfunction of the liver leads to various diseases. Nonalcoholic fatty liver disease is rapidly becoming a major health concern worldwide and is characterized by abnormal retention of excess lipids in the liver. CCCTC-binding factor (CTCF) is a highly conserved zinc finger protein that regulates higher-order chromatin organization and is...

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Identifiers

PMID: 34358714
DOI: 10.1016/j.jcmgh.2021.07.016
PMCID: PMC8551791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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