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RNAseq analysis reveals transcriptome changes associated with the progression of non-alcoholic liver disease in livers from <i>Efcab4b</i> knockout mice

2024-05-15

Abstract excerpt

<h4>ABSTRACT</h4> EFCAB4B is an evolutionarily conserved protein that encodes for the Rab GTPase Rab46, and the CRAC channel modulator, CRACR2A. Previous genome wide association studies have demonstrated the association of EFCAB4B variants in the progression of non-alcoholic liver disease (NAFLD). In this study we show that mice with global depletion of Efcab4b -/- have significantly larger livers than their w...

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Literature Corpus work
2f2d4214-07d7-578d-832d-48643f17583b
DOI
10.1101/2024.05.13.593681
Open publication

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RNAseq analysis reveals transcriptome changes associated with the progression of non-alcoholic liver disease in livers from <i>Efcab4b</i> knockout miceDOI 10.1101/2024.05.13.593681
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