Article

Single-cell analysis of non-alcoholic fatty livers identifies a role for the constitutive androstane receptor

2022-08-15

Abstract excerpt

<h4>ABSTRACT</h4> Non-alcoholic fatty liver disease is a heterogeneous disease with unclear underlying molecular mechanisms. While several genetic risk factors have been identified, the cellular and molecular heterogeneity associated with the development of hepatic steatosis are still not fully understood. Here, we perform single-cell RNA sequencing of hepatocytes and hepatic nonparenchymal cells to map the lipid...

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Literature Corpus work: d5a6469e-dc04-5544-ae57-a8d1d58fb7e5
DOI: 10.1101/2022.08.15.504026

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