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Article

C/EBPβ transcription factor promotes alcohol-induced liver fibrosis in males via HDL remodeling

19 Feb 2025

Abstract excerpt

BACKGROUND: Alcohol-associated liver disease (ALD) is the main cause of alcohol-associated mortality. However, the mechanism of ALD development is poorly understood. Epigenetic changes are thought to play an important role in ALD. We aimed to define the epigenetic changes induced by alcohol and predict drivers of these changes. METHODS: Mice were fed high-fat diet with or without 20% of alcohol in the drinking...

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PMID: 39969482
DOI: 10.1097/hc9.0000000000000645

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