Article

Antigenic drift expands viral escape pathways from imprinted host humoral immunity

2024-03-23

Abstract excerpt

<h4>ABSTRACT</h4> An initial virus exposure can imprint antibodies such that future responses to antigenically drifted strains are dependent on the identity of the imprinting strain. Subsequent exposure to antigenically distinct strains followed by affinity maturation can guide immune responses toward generation of cross-reactive antibodies. How viruses evolve in turn to escape these imprinted broad antibody resp...

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Literature Corpus work: ae74cfee-2454-5cf1-8622-c46fa164554c
DOI: 10.1101/2024.03.20.585891

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