Article
Immune imprinting: The persisting influence of the first antigenic encounter with rapidly evolving viruses
16 Aug 2024
Abstract excerpt
Immune imprinting is a phenomenon that stems from the fundamentals of immunological memory. Upon recurrent exposures to an evolving pathogen, the immune system must weigh the benefits of rapidly recalling established antibody repertoires with greater affinity to the initial variant or invest additional time and energy in producing de novo responses specific to the emerging variant. In this review, we delve into...
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