Longitudinal analysis of drift in the circulating human antibody repertoire over four years

Abstract excerpt

<h4>ABSTRACT</h4> The human immune system is a sophisticated network of cells and molecules that plays a vital role in safeguarding the body against a broad range of foreign agents. One of the key components of the immune system is the circulating antibody repertoire, a vast collection of different antibodies that recognize and eliminate foreign agents specifically. The diversity and specificity of the circulatin...

Topics

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• Antibodies
• Clone Cells
• Healthy Volunteers
• Immune Cell Function and Interaction
• Monoclonal and Polyclonal Antibodies Research
• T-cell and B-cell Immunology
• V(D)J Recombination
• Vaccination

Identifiers and source

Literature Corpus work

ef867649-1bbb-559e-a532-537471dfdd69

DOI

10.1101/2025.03.20.644446