Article

IFN-α Induces Heterogenous ROS Production in Human β-Cells

2025-02-20

Abstract excerpt

<h4>ABSTRACT</h4> Type 1 diabetes (T1D) is a multifactorial disease involving genetic and environmental factors, including viral infection. We investigated the impact of interferon alpha (IFN-α), a cytokine produced during the immune response to viral infection or the presence of un-edited endogenous double-stranded RNAs, on human β-cell physiology. Intravital microscopy on transplanted human islets using a β-cel...

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Literature Corpus work: ae6c8ccd-8f5d-5bbc-a0bc-0eba2f92b775
DOI: 10.1101/2025.02.19.639120

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