Article

Characterisation of native human pancreatic mesenchymal stromal cells in type 1 diabetes

2025-03-11

Abstract excerpt

Aims/hypothesis: Culture-expanded mesenchymal stromal cells (MSCs) reduce immune cell activation and improve islet functional survival. However, little is known about native human pancreatic MSCs (npMSCs) in health or how they are altered in type 1 diabetes. Here, we determined the number, density and islet-protective phenotype of npMSCs in situ in control individuals and those with type 1 diabetes. <h4>Methods:</...

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Literature Corpus work: 0ee964f0-e079-5568-a74b-a56cce896415
DOI: 10.1101/2025.03.05.641596

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