Article

Diverse mutations and structural variations contribute to Notch signaling deregulation in paediatric T-cell lymphoblastic lymphoma

2022-05-04

Abstract excerpt

<h4>Background: </h4> T-cell lymphoblastic lymphoma (T-LBL) is an aggressive neoplasm closely related to T-cell acute lymphoblastic leukaemia (T-ALL). Despite their similarities, and contrary to T-ALL, studies on pediatric T-LBL are scarce and, therefore, its molecular landscape has not been fully elucidated yet. Procedure To characterize the genetic and molecular heterogeneity of paediatric T-LBL, 33 patients wer...

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Literature Corpus work: ae0ac650-ed11-5f0a-b3cb-58b8e5f2b960
DOI: 10.22541/au.165165320.05970525/v1

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