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Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma.

Blood - 4 Jul 2024

Kroeze Emma, Iaccarino Ingram, Kleisman Michelle M, Mondal Mayukh, Beder Thomas, Khouja Mouhamad, Höppner Marc P, Scheijde-Vermeulen Marijn A, Kester Lennart A, Brüggemann Monika, Baldus Claudia D, Cario Gunnar, Bladergroen Reno S, Garnier Nathalie, Attarbaschi Andishe, Verdu-Amorós Jaime, Sutton Rosemary, Macintyre Elizabeth, Scholten Kenneth, Arias Padilla Laura, Burkhardt Birgit, Beishuizen Auke, den Boer Monique L, Kuiper Roland P, Loeffen Jan L C, Boer Judith M, Klapper Wolfram

Abstract excerpt

ABSTRACT: Pediatric B-cell precursor (BCP) lymphoblastic malignancies are neoplasms with manifestation either in the bone marrow or blood (BCP acute lymphoblastic leukemia [BCP-ALL]) or are less common in extramedullary tissue (BCP lymphoblastic lymphoma [BCP-LBL]). Although both presentations are similar in morphology and immunophenotype, molecular studies have been virtually restricted to BCP-ALL so far. The...

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Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

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PMID: 38588489
DOI: 10.1182/blood.2024023938

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