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The Physiopathology of T- Cell Acute Lymphoblastic Leukemia: Focus on Molecular Aspects

28 Feb 2020

Abstract excerpt

T-cell acute lymphoblastic leukemia/lymphoma is an aggressive hematological neoplasm whose classification is still based on immunophenotypic findings. Frontline treatment encompass high intensity combination chemotherapy with good overall survival; however, relapsing/refractory patients have very limited options. In the last years, the understanding of molecular physiopathology of this disease, lead to the...

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PMID: 32185137
DOI: 10.3389/fonc.2020.00273

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