Article

SLC44A1 deficiency impedes myelin development in the central nervous system

2025-04-09

Abstract excerpt

Axon-wrapping myelin sheath is essential for the proper functioning of the central nervous system (CNS). Defects in myelination occur in various neurodevelopmental disorders. Human deficiency of the solute carrier 44A1 (SLC44A1) causes a new type of childhood-onset neurodegeneration with leukoencephalopathy. Currently, there is no effective treatment for this devastating disease, and little is known about its path...

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Literature Corpus work: ada0d59c-7ad4-5c55-8d56-bff0a9c4fdc0
DOI: 10.1101/2025.04.08.647819

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