Article

Oligodendrocytes form paranodal bridges that generate chains of myelin sheaths that are vulnerable to degeneration with age

2022-02-17

Abstract excerpt

<h4>ABSTRACT</h4> Myelin sheaths in the CNS are generated by the tips of oligodendrocyte processes, which wrap axons to accelerate action potential conduction, provide metabolic support and control excitability. Here we identify a distinct mode of myelination, conserved between zebrafish, mouse and human, in which oligodendrocytes extend myelin along individual axons by linking myelin sheaths across nodes of Ranv...

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Literature Corpus work: a5a4bf70-a80e-5f2a-8717-12eb28411b27
DOI: 10.1101/2022.02.16.480718

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