Article

Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer’s disease mouse model: a role for ER-mitochondria interaction

2022-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Deregulation of protein synthesis and ER stress/unfolded protein response (ER stress/UPR) have been reported in astrocytes. However, the relationships between protein synthesis deregulation and ER stress/UPR, as well as their role in the altered homeostatic support of Alzheimer’s disease (AD) astrocytes remain poorly understood. Previously, we reported that in astrocytic cell lines from 3xTg-AD...

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Literature Corpus work: ad69eece-8360-5c6f-a091-0835762e3f52
DOI: 10.1101/2022.03.24.485644

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