Article

High-throughput variant detection using a color-mixing strategy

2021-07-01

Abstract excerpt

<h4>ABSTRACT</h4> Many diseases are related to multiple genetic alterations along a single gene. Probing for highly multiple (>10) variants in a single qPCR tube is not possible due to a limited number of fluorescence channels and one variant per channel, so many more tubes are needed. Here, we experimentally validate our novel color-mixing strategy that uses fluorescence combinations as digital color codes to pr...

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Literature Corpus work: acd26633-e5a3-5e4a-a2db-1dc91ba667be
DOI: 10.1101/2021.06.30.450651

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