Back to search

Article

Glycan-Based Shaping Of The Microbiota During Primate Evolution

2021-02-10

Abstract excerpt

Genes encoding certain glycosyltransferases are thought to be under relatively high selection pressure, due to the involvement of the glycans that they synthesize in host-microbe interactions. Here we used a mouse model to investigate whether the loss of α-1,3-galactosyltransferase ( GGTA1 ) function and Galα1-3Galβ1-4GlcNAcβ1-R (αGal) expression during primate evolution might have affected host-microbiota intera...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
acc937aa-032a-5217-814b-7670e4be88bc
DOI
10.1101/2021.02.10.430443
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Glycan-Based Shaping Of The Microbiota During Primate EvolutionDOI 10.1101/2021.02.10.430443
Expression of the blood-group-related glycosyltransferase <i>B4galnt2</i> influences the intestinal microbiota in miceSemantic proximity
A trade-off between resistance to infection and reproduction in primate evolutionSemantic proximity
Distribution of Bacterial α1,3-Galactosyltransferase Genes in the Human Gut MicrobiomeSemantic proximity
The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious diseaseSemantic proximity
Bacterial Colonization and TH17 Immunity are Shaped by Intestinal Sialylation in Neonatal MiceSemantic proximity
IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgMSemantic proximity
Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiotaSemantic proximity
Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis.Semantic proximity
IgA-deficient humans exhibit gut microbiota dysbiosis despite production of compensatory IgMSemantic proximity
Multigenerational Influences of the Fut2 Gene on the Dynamics of the Gut Microbiota in MiceSemantic proximity
Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection.Semantic proximity
The Formation of Glycan-Specific Natural Antibodies Repertoire in GalT-KO Mice Is Determined by Gut MicrobiotaSemantic proximity
Select a neighboring publication to make it the new centre.