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Article

Expression of the blood-group-related glycosyltransferase <i>B4galnt2</i> influences the intestinal microbiota in mice

26 Jan 2012

Abstract excerpt

Glycans on mucosal surfaces have an important role in host-microbe interactions. The locus encoding the blood-group-related glycosyltransferase β-1,4-N-acetylgalactosaminyltransferase 2 (B4galnt2) is subject to strong selective forces in natural house-mouse populations that contain a common allelic variant that confers loss of B4galnt2 gene expression in the gastrointestinal (GI) tract. We reasoned that altered...

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PMID: 22278669
DOI: 10.1038/ismej.2011.204

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