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Article

Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection.

PLoS pathogens - 1 Jul 2015

Rausch Philipp, Steck Natalie, Suwandi Abdulhadi, Seidel Janice A, Künzel Sven, Bhullar Kirandeep, Basic Marijana, Bleich Andre, Johnsen Jill M, Vallance Bruce A, Baines John F, Grassl Guntram A

Abstract excerpt

Glycans play important roles in host-microbe interactions. Tissue-specific expression patterns of the blood group glycosyltransferase β-1,4-N-acetylgalactosaminyltransferase 2 (B4galnt2) are variable in wild mouse populations, and loss of B4galnt2 expression is associated with altered intestinal microbiota. We hypothesized that variation in B4galnt2 expression alters susceptibility to intestinal pathogens. To...

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Identifiers

PMID: 26133982
DOI: 10.1371/journal.ppat.1005008
PMCID: PMC4489644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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