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The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease

25 Feb 2021

Abstract excerpt

The glycosylation profile of the gastrointestinal tract is an important factor mediating host-microbe interactions. Variation in these glycan structures is often mediated by blood group-related glycosyltransferases, and can lead to wide-ranging differences in susceptibility to both infectious- as well as chronic disease. In this review, we focus on the interplay between host glycosylation, the intestinal...

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PMID: 33662872
DOI: 10.1016/j.ijmm.2021.151487

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