Article

Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation

2024-07-08

Abstract excerpt

<h4>Summary</h4> Adult-type diffuse gliomas, the most common primary brain tumors, pose significant clinical challenges due to limited treatment options, restricted anti-tumor immune response and dismal patient prognosis. In this study, we elucidate the immunological function and clinical relevance of intra-tumoral tertiary lymphoid structures (TLS) in adaptive anti-glioma immunity. We conducted a comprehensive,...

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Literature Corpus work: acc32c59-5a4a-5b24-9b55-81f52fadec39
DOI: 10.1101/2024.07.04.602038

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