Article

Identification and characterization of tertiary lymphoid structures in brain metastases

2024-10-01

Abstract excerpt

<h4>Summary</h4> Brain metastases (BrM) are the most common cancers in the brain. We performed transcriptome-wide gene expression profiling combined with spatial immune cell profiling to characterize the tumor immune microenvironment in BrM from different primary tumors. We found that BrM from lung carcinoma and malignant melanoma showed overall higher immune cell infiltration as compared to BrM from breast carci...

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Literature Corpus work: 14a1b5f1-252e-5046-9200-0cdf9b0ab327
DOI: 10.1101/2024.09.30.614674

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