Article

Lineage and Spatial Mapping of Glioblastoma-associated Immunity

2020-06-02

Abstract excerpt

<h4>Summary</h4> The diversity of molecular states and cellular plasticity of immune cells in the glioblastoma environment is still poorly understood. Here, we performed scRNA sequencing of the immune compartment and mapped potential cellular interactions leading to an immunosuppressive microenvironment and dysfunction of T cells. Through inferring the dynamic adaptation during T cell activation, we identified th...

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Literature Corpus work: 9a37693d-07b9-5c89-95f7-34dc547888fa
DOI: 10.1101/2020.06.01.121467

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