Article

Decoding the immune response in leptomeningeal disease through single-cell sequencing of cerebrospinal fluid

2025-01-27

Abstract excerpt

Assessing anti-tumor immune responses and immune microenvironments in central nervous system (CNS) neoplasms, such as brain tumors and leptomeningeal disease (LMD), provides prognostic insights and predictive biomarkers. Liquid biopsy of the cerebrospinal fluid (CSF) represents a promising minimally-invasive approach, but its ability to reflect immune responses against tumors remains unclear. Here, we used single-...

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Literature Corpus work: d5069566-39ba-5274-8573-3f10cc159ccb
DOI: 10.1101/2025.01.27.634744

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