Article

Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma

2024-07-06

Abstract excerpt

Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates associated with improved prognosis in numerous tumors. To date, their prognostic value in central nervous system cancers and the events underlying their formation remain unclear. Here, we find that TLS correlate with improved survival in glioblastoma patients. Furthermore, combining spatial transcriptomics of human tissues with longitudinal studies...

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Literature Corpus work: 23426910-0a73-5a11-aaed-6d62300a81bc
DOI: 10.1101/2024.07.04.601824

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