Article

Effects of translocations on transcription from PVT.

1990-04-01

Abstract excerpt

We have previously described a transcription unit on human chromosome 8, designated as PVT, that is consistently disrupted by the minority forms of translocations [t(2;8) and t(8;22)] in Burkitt's lymphoma. PVT begins 57 kilobase pairs downstream of the proto-oncogene MYC and is more than 200 kilobase pairs in length. In order to explore the pathogenic impact of translocations affecting PVT, we have characterized...

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Literature Corpus work: ac986d8d-1299-522b-a756-85b24bf04e63
DOI: 10.1128/mcb.10.4.1835

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