Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases.

doi:10.1046/j.1365-2141.2000.02241.x

Article

Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases.

British journal of haematology - 1 Sept 2000

Cario G, Stadt U Z, Reiter A, Welte K, Sykora K W

Abstract excerpt

Burkitt's lymphoma/Burkitt cell leukaemia (BL) is characterized by one of the reciprocal translocations involving the MYC oncogene on chromosome 8 and one of the immunoglobulin (Ig) loci on chromosomes 14, 2 or 22. In the few cell lines with the variant translocations t(2;8) and t(8;22) reported to date, the breakpoints on chromosome 8 were located downstream of MYC at a distance of up to 300 kb and more. Here,...

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Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases.

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Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases.

Abstract excerpt

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